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Organic gems like ibetan wood mala, pearls, coral, and amber should simply be wiped clean with moist cloth. Due to their organic nature, these gems both are soft and porous. Be careful about chemicals in hairspray, cosmetics, or perfume: they will, with time, damage pearls especially. Opals also require special care. Never work with an ultrasonic, never use ammonia, and get away from heat and strong light.
Opaque gemstones like tibetan lotus flower bracelet, lapis lazuli, turquoise, malachite, require special care as they are rocks, not crystals of a single mineral like transparent gems. There gem materials should just be wiped clean gently that has a moist cloth. These gemstones might be porous and might absorb chemicals, even soap, and in addition they may develop inside the stone and discolor it. Never use and ultrasonic cleaner and not use ammonia or any chemical solution.
A little care and wise practice can add life, luster and longevity for your precious jewelry and gems. Protect neglect the by following the above mentioned guidelines.